MicroRNA-146a rs2910164 G/C polymorphism and gastrointestinal cancer susceptibility: A meta-analysis based on East Asian population
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چکیده
منابع مشابه
Meta-Analysis of MicroRNA-146a rs2910164 G>C Polymorphism Association with Autoimmune Diseases Susceptibility, an Update Based on 24 Studies
BACKGROUND Published data showed that the susceptibility of autoimmune diseases (ADs) was associated with the polymorphism rs2910164 in microRNA-146a (miR-146a). However, the results remain controversial so far. Two meta-analyses published in 2013 and 2014 came to opposite conclusions. In order to derive a more precise estimation of the relationship, we performed this meta-analysis. METHODS W...
متن کاملAssociation between microRNA-196a2 rs11614913, microRNA-146a rs2910164, and microRNA-423 rs6505162 polymorphisms and esophageal cancer risk: A meta-analysis
Many observational studies have found that microRNA-196a2 rs11614913, microRNA-146a rs2910164, and microRNA-423 rs6505162 are associated with esophageal cancer risk. However, the results were mixed and inconsistent among these studies. We conducted a meta-analysis to assess the relationship between the polymorphisms of three microRNAs and esophageal cancer susceptibility. We systematically sear...
متن کاملAssociation of MicroRNA-146a rs2910164 Gene Polymorphism with Metabolic Syndrome.
Alteration in microRNA-146a (miRNA-146a) expression is an important event in the pathogenesis of many human diseases. MiRNA-146a rs2910164 is a functional polymorphism that showed association with several diseases. Metabolic syndrome is an aggregation of multiple risk factors including impaired glucose tolerance, increased highdensity lipoprotein, abdominal obesity, and high blood pressure. The...
متن کاملAssociation of miR-146a rs2910164 and miR-27a rs895819 polymorphisms with type 2 diabetes susceptibility: A Meta-Analysis
Background and Aim: Several investigations have evaluated the association of miR-146a rs2910164 and miR-27a rs895819 single-nucleotide polymorphisms with susceptibility to type 2 diabetes (T2D). However, the findings are conflicting and inconclusive. Therefore, this meta-analysis performed to investigate the association between these polymorphisms and T2D risk. Methods: Studies were identifie...
متن کاملEffects of Common Polymorphisms rs11614913 in miR-196a2 and rs2910164 in miR-146a on Cancer Susceptibility: A Meta-Analysis
BACKGROUND MicroRNAs regulate gene expression at the post-transcriptional level and involved in diverse biological and pathological processes, including tumorigenesis. Rs11614913 in miR-196a2 and rs2910164 in miR-146a are shown to associate with increased/decreased cancer risk. We performed a meta-analysis to systematically summarize the possible association. METHODOLOGY/PRINCIPAL FINDINGS We...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Therapeutics
سال: 2014
ISSN: 0973-1482
DOI: 10.4103/0973-1482.151462